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A meta-analysis by Cazzola et al., published in the European Respiratory Review , focused specifically on NAC and found that patients treated with NAC had significantly fewer exacerbations of chronic bronchitis or COPD (relative risk 0.75, 95% CI 0.66 to 0.84)

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This can cause serious respiratory issues, including pneumonia and other infections, and may require medical intervention

Cystathionine -lyase Deficiency Mediates Neurodegeneration in Huntington's Disease